Compliance with prescribed drug regimens is particularly important among th
e elderly because of their increased vulnerability and greater burden of ch
ronic disorders. This narrative review discusses the factors that are impor
tant to compliance, with particular reference to the elderly. These factors
are the patient's perceptions of his disease and it's treatment, the physi
cian's perceptions, the manner the physician assumes and the language he us
es to communicate with the patient, the patient's living situation, regular
medication review, and a continuity of health care provision. Since it is
the patient who decides how to use the therapy, his or her involvement in t
he process of explaining and understanding it is the key to improved compli
ance.