The cost of parenteral admixtures has an important impact on the hospital b
udget. Recently, a Viaflex(R) with vial adapter (named 'minibag plus' in so
me countries) has been commercialized in order to facilitate parenteral adm
ixture preparation. In the present study a preparation using Viaflex(R) wit
h a vial adapter has been economically compared with a preparation with a t
raditional Viaflex(R) (without adapter) in a centralized unit or in nursing
wards in a unit-dose drug distribution system. A cost-analysis was conduct
ed from the hospital point of view. Direct costs were considered: these inc
luded supplies and human resources. Differences in the whole process betwee
n the two types of Viaflex(R) were analysed. The process included: purchasi
ng, reception, storage, medical order record, preparation in the Pharmacy S
ervice (PS), delivery from the PS to the nursing unit, preparation by the n
urse, return of unused material to the PS. Human resource costs were estima
ted by time counting and multiplying by the average salary. To estimate was
ted material, drug and supplies delivered from the PS and returned to the P
S were counted during 26 days. With the new Viaflex(R) costs are reduced by
30% in comparison with drug dilution using the traditional Viaflex(R) in a
centralized unit of the PS, and by 13.4% in comparison with preparation wi
th the traditional Viaflex(R) in the nursing ward. In addition it can be es
timated that contamination risk with the new Viaflex(R) is lower than prepa
ration in the nursing ward with the traditional Viaflex(R). Therefore, owin
g to its lower cost we recommend the use of Viaflex(R) with vial adapter fo
r drug dilution for those vials that are compatible with the system.