A pupil and then the successor of Vesalius to the Chair of Anatomy and
Surgery at the University of Padua, Matteo Realdo Colombo (1516-1559)
was equally consumed by the flame of scientific inquiry and recogniti
on. His sole contribution to the literature, De Re Anatomica, was publ
ished after his death in 1559. In it, he correctly describes the posit
ion of the right kidney as lower than that of the left and provides th
e best description of the pulmonary circulation before that of William
Harvey, who in his text duly acknowledged Colombo's contributions. In
the concluding chapter, he establishes the beginnings of morbid anato
my in describing diseased organs. De Re Anatomica was widely used as a
textbook of anatomy, being translated into English in 1578 and German
in 1609. He came to be sufficiently well known to become physician to
the Vatican. One of his best known patients was Michelangelo, with wh
om he vainly tried to collaborate in illustrating De Re Anatomica. A r
egrettable eventuality, which could have reversed the fortunes of Vesa
lius and Colombo in the annals of the history of medicine.