Transesophageal echocardiographic assessment of hemodynamic function during laparoscopic cholecystectomy in healthy patients

Background: This study aimed by means of transesophageal echocardiography, to evaluate hemodynamic changes induced by pneumoperitoneum in patients wit h normal cardiac performance. Methods: In this study, 11 ASA I-II patients (mean age, 39 years) with norm al cardiac performance undergoing laparoscopic cholecystectomy were evaluat ed. A 5-MHz transesophageal biplane phased-array transducer connected to an echocardiographer was inserted after induction of anesthesia. Data were co llected at three different times: before insufflation (T1), 10 min after in sufflation (T2), and 5 min after desufflation (T3). At these same times, he art rate, systolic blood pressure, diastolic blood pressure, end-tidal carb on dioxide (CO2), and peak airway pressure were recorded. Statistical analy sis was performed using one-way and two-way analysis of variance (ANOVA), A p value less than 0.05 was considered significant. Results: End-systolic and end-diastolic diameters of the left ventricle, co ntractility, and performance parameters did not change significantly, Conve rsely, at insufflation, color Doppler area of the mitral backflow increased significantly (p < 0.05) when already present or showed up abruptly (T1: 0 .22 +/- 0.28 cm(2): T2: 1.28 +/- 1.02 cm(2); T3: 0.49 +/- 0.53 cm(2)). Conclusions: Such an event is not interpreted as a mitral insufficiency. It is possibly the result of a "contrast effect" caused by the absorption of CO2 microbubbles in the blood.