Activated pyrroles from pyridazines: nitrogen extrusion by electroreduction

Authors
Manh, GT Hazard, R Pradere, JP Tallec, A Raoult, E Dubreuil, D
Citation
Gt. Manh et al., Activated pyrroles from pyridazines: nitrogen extrusion by electroreduction, TETRAHEDR L, 41(5), 2000, pp. 647-650
Citations number
16
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
5
Year of publication
2000
Pages
647 - 650
Database
ISI
SICI code
0040-4039(20000129)41:5<647:APFPNE>2.0.ZU;2-A
Abstract
The bielectronic electrochemical reduction of pyridazines, substituted by e lectron-withdrawing groups, leads to their corresponding 1,2-dihydro deriva tives. Depending on the nature of the ring substitution, these intermediate s can either rearrange into 1,4-dihydropyridazine isomers or be further ele ctrochemically reduced into activated pyrroles. (C) 2000 Published by Elsev ier Science Ltd. All rights reserved.