Fast ester cleavage of sterically hindered alpha- and beta-aminoesters under non-aqueous conditions. Application to the kinetic resolution of aziridine esters

Authors
Alezra, V Bouchet, C Micouin, L Bonin, M Husson, HP
Citation
V. Alezra et al., Fast ester cleavage of sterically hindered alpha- and beta-aminoesters under non-aqueous conditions. Application to the kinetic resolution of aziridine esters, TETRAHEDR L, 41(5), 2000, pp. 655-658
Citations number
7
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
5
Year of publication
2000
Pages
655 - 658
Database
ISI
SICI code
0040-4039(20000129)41:5<655:FECOSH>2.0.ZU;2-T
Abstract
Various protected alpha- and beta-aminoesters undergo fast eater cleavage b y treatment with t-BuOK in THE The accelerating effect of a neighboring che lating group was used for the efficient kinetic resolution of non-racemic a ziridine esters. (C) 2000 Elsevier Science Ltd. All rights reserved.