Poly(3,4-alkylenedioxypyrrole)s as highly stable aqueous-compatible conducting polymers,vith biomedical implications

Citation
Ca. Thomas et al., Poly(3,4-alkylenedioxypyrrole)s as highly stable aqueous-compatible conducting polymers,vith biomedical implications, ADVAN MATER, 12(3), 2000, pp. 222
Citations number
20
Categorie Soggetti
Multidisciplinary,"Material Science & Engineering
Journal title
ADVANCED MATERIALS
ISSN journal
09359648 → ACNP
Volume
12
Issue
3
Year of publication
2000
Database
ISI
SICI code
0935-9648(20000203)12:3<222:PAHSAC>2.0.ZU;2-Q
Abstract
Polypyrrole (PPy) may be set to revolutionize biological applications such as tissue engineering and biosensors due to its high electroactivity/conduc tivity and the water compatibility of its films. However, inherent weakness es in PPy-based materials arise from defect sites along the PPy polymer bac kbone, and its instability to reduction by biologically relevant reducing a gents such as dithiothreitol (DTT) and glutathione. Here is presented a fam ily of electron-rich poly(3,4-alkylenedioxypyrrole)s that address these str uctural weaknesses and are stable in the conducting, oxidized form, renderi ng them immune to strong biological reducing agents.