Se. Cohen et al., Walking with labor epidural analgesia - The impact of bupivacaine concentration and a lidocaine-epinephrine test dose, ANESTHESIOL, 92(2), 2000, pp. 387-392
Citations number
15
Categorie Soggetti
Aneshtesia & Intensive Care","Medical Research Diagnosis & Treatment
Background: Regional analgesia techniques for labor that permit ambulation
are popular among parturients, This study evaluated the influence of bupiva
caine bolus concentration and a 3-ml 1.5% lidocaine-epinephrine test dose,
on analgesic effectiveness and the ability to walk after block placement.
Methods: Using a randomized double-blind study design, epidural analgesia w
as initiated in 60 parturients undergoing labor as follows: Group TD/B.0625
received a 3-ml lidocaine-epinephrine test dose + 12 ml bupivacaine, 0.062
5%; group TD/ B.125 received a 3-ml test dose + 12 mi bupivacaine, 0.125%;
group B,0625 received 15 mi bupivacaine, 0.0625% (no test dose); and group
B,125 received 15 mi bupivacaine, 0.125% (no test dose). Initial boluses in
all groups contained 10 mu g sufentanil. Bupivacaine, 0.0625%, with 0.33 m
u g/ml sufentanil was infused throughout labor at 13.5--15 ml/h. Analgesia
balance, proprioception, motor block, and patient ability to stand and walk
were evaluated at various intervals.
Results: A bolus of 0.125% bupivacaine containing sufentanil, without a pre
vious test dose, proved to be optimal with respect to analgesia and early a
mbulation. When a test dose was given before bupivacaine, 0,125%, fewer wom
en walked within 1 h of block placement. Bupivacaine, 0.0625%, with sufenta
nil, with or without a test dose, provided inadequate analgesia, necessitat
ing additional bupivacaine, which impaired the ability to walk. A high perc
entage of women in all groups (73-33%) walked at some stage during labor.
Conclusions: Omitting a lidocaine-epinephrine test dose and using 0.125% bu
pivacaine for the initial bolus should permit ambulation in the early postb
lock period for most parturients who elect this option.