Effects of 100 mT time varying magnetic fields on the growth of tumors in mice

The effects of 100-mT, 0.8-Hz square-wave magnetic fields on the growth of chemically induced tumors in mice were investigated. Tumors were initiated using one injection of benzo(a)pyrene (either 0.2 mg or 2.0 mg/animal). Mal e and female mice (Balb/c, C3H and C57/bl/6 strains) were exposed for 8h/da y from the onset of tumor until death or until the tumor volume reached a p redetermined volume. Statistically significant decrease in the rate of tumo r growth and increase in survival were observed in all cases. Results are d iscussed in terms of previous published work and of possible mechanisms. (C ) 2000 Wiley-Liss, Inc.