Assessment of various treatments to reduce carriage of Salmonella in swine

In this study, different strategies to reduce carriage of Salmonella spp. i n pigs were evaluated. Probiotics, prebiotics, vaccination, and acidificati on of drinking water were assessed as means of reducing Salmonella. Acidifi cation of water, use of egg yolk specific immunoglobulins, and vaccination with an endotoxin vaccine did not reduce Salmonella excretion in experiment ally infected pigs. A reduction of Salmonella in the colonization of mesent eric lymph nodes was observed with the use of bambermycins and a live atten uated vaccine. A reduction in the shedding of S. Typhimurium was also obser ved after supplementation with fructooligosaccharides in drinking water. Th e use of probiotics and prebiotics appeared to change the pig fecal bacteri al flora as indicated by Gram staining of smears from rectal swabs.