Synthesis of a tetrasaccharide representing a minimal epitope of an arabinogalactan

Authors
Du, YG Pan, QF Kong, FZ
Citation
Yg. Du et al., Synthesis of a tetrasaccharide representing a minimal epitope of an arabinogalactan, CARBOHY RES, 323(1-4), 2000, pp. 28-35
Citations number
17
Categorie Soggetti
Agricultural Chemistry","Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
CARBOHYDRATE RESEARCH
ISSN journal
00086215 → ACNP
Volume
323
Issue
1-4
Year of publication
2000
Pages
28 - 35
Database
ISI
SICI code
0008-6215(20000112)323:1-4<28:SOATRA>2.0.ZU;2-S
Abstract
The hydrophobic alkyl chain-containing tetrasaccharide, dodecyl beta-D-gala ctopyranosyl-(1 --> 6)-beta-D-galactopyranosyl-(1 --> 6)-[alpha-L-arabinofu ranosyl-(1 --> 2)]-beta-D-galactopyranoside, was synthesized efficiently us ing a convergent strategy. In coupling reactions, protected trichloroacetim idates proved to be better donors than their corresponding bromides in the preparation of the dodecyl disaccharide and trisaccharide. Zemplen deacylat ion provided the target tetramer in good overall yield. (C) 2000 Elsevier S cience Ltd. AU rights reserved.