I. Spanik et J. Krupcik, The use of cyclodextrin and their derivatives as stationary phases for separation of enantiomers by capillary gas chromatography, CHEM LISTY, 94(1), 2000, pp. 10-14
The review deals with the use of cyclodextrins (CD) and their derivatives a
s stationary phases in gas chromatography for separation of enantiomers of
organic substances. Unlike the native cyclodextrins, their alkyl, acyl and
tert-butyl(tri-methyl)silyl derivatives are successfully used as stationary
phases in capillary gas chromatography. The enantioselectivity of the CD d
erivatives can be changed both by the nature of silyl substituents and by t
he type of CDs. alpha-, beta- and gamma-CD derivatives with bulkier substit
uents in positions 2 and 3 than in position 6 exhibit a specific enantiosel
ectivity compared with those containing equal substituents.