Biliary disease occurs in a subset of AIDS patients with CD4 counts of
less than 100 per mm(3). These patients present with right upper quad
rant and epigastric pain, cholestasis, and usually abnormal findings o
n imaging. In 75% of patients, an associated opportunistic infection c
an be identified. In patients with biliary disease, pain is often reli
eved following endoscopic sphincterotomy, whereas cholecystectomy prov
ides pain relief in patients with acalculous cholecystitis.