DETERMINATION OF TETRACYCLINES IN BONES, MECHANICALLY SEPARATED BEEF,AND BONES BY HPLC METHOD AND MICROBIOLOGICAL AGAR DIFFUSION TESTS

Citation
L. Korimova et al., DETERMINATION OF TETRACYCLINES IN BONES, MECHANICALLY SEPARATED BEEF,AND BONES BY HPLC METHOD AND MICROBIOLOGICAL AGAR DIFFUSION TESTS, Veterinarni medicina, 42(5), 1997, pp. 129-131
Citations number
14
Categorie Soggetti
Veterinary Sciences
Journal title
ISSN journal
03758427
Volume
42
Issue
5
Year of publication
1997
Pages
129 - 131
Database
ISI
SICI code
0375-8427(1997)42:5<129:DOTIBM>2.0.ZU;2-P
Abstract
HPLC method with solid phase extraction, and microbiological agar diff usion tests for determination of oxytetracycline (OTC), tetracycline ( TC) and chlortetracycline (CTC) in bones, mechanically separated beef and bones were developed. Both mechanically separated bones End bovine flat bones showed the highest yield of tetracyclines by HPLC method. Among tetracyclines, the highest yield was determined in chlortetracyc line. The strains of Bacillus subtilis (PH 6.0) and B. stearothermophi lus showed the highest sensitivity to the presence of tetracyclines.