Objective: To evaluate whether the presence of antiphospholipid antibodies
among women undergoing IVF affects the likelihood of IVF success.
Design: A meta-analysis of seven eligible studies on antiphospholipid antib
odies and IVF outcome.
Main Outcome Measure(s): Odds ratios (ORs) and 95% confidence intervals (CI
s) of an association between the presence of antiphospholipid antibodies an
d both clinical pregnancy and live birth from IVF.
Result(s): There was no significant association between antiphospholipid ab
normalities and either clinical pregnancy (OR 0.99: 95% CI 0.64-1.53) or li
ve birth (OR 1.07; 95% CI 0.66-1.75) in IVF patients.
Conclusion(s): The measurement of antiphospholipid antibodies is not warran
ted in patients undergoing IVF. (Fertil Steril(R) 2000;73:330-3. (C)2000 by
American Society for Reproductive Medicine.).