The purpose of this study was to examine the relations among patients' perc
eptions of their physicians' communicative behavior during the informed con
sent interview, the patient's feeling of being confirmed by the physician a
nd satisfied with care delivered by the physician, and the patient's decisi
on to participate in a clinical trial or not. Respondents included 130 canc
er patients who were eligible for a clinical trial and who had recently dis
cussed trial participation with their physicians. Results indicated that a
linear combination of the variables physician affiliative style, physician
dominant or controlling style, patient satisfaction, patient confirmation,
patient preference for decision making, patient desire for information, and
patient age discriminate between patients who agree to participate in clin
ical trials and patients who refuse to participate. Physicians' affiliative
communicative behaviors and patient satisfaction were clearly important to
patients who agreed to participate. Motivations for patients who declined
to participate in trials were less clear. Implications for physicians who o
ffer clinical trials to their patients are that specific communication skil
ls may enhance their patients' satisfaction and may help increase enrollmen
t in clinical trials.