T. Ebner et al., Prognostic value of first polar body morphology on fertilization rate and embryo quality in intracytoplasmic sperm injection, HUM REPR, 15(2), 2000, pp. 427-430
The association between oocyte morphology and subsequent fertilization rate
and embryo quality in intracytoplasmic sperm injection (ICSI) is subject t
o considerable controversy: This retrospective study was carried out to inv
estigate a possible prognostic value of first polar body morphology with re
gard to fertilization rate and embryo quality. A total of 70 consecutive IC
SI cases was included in this study. The results showed that classification
based on first polar body morphology revealed a significant correlation wi
th fertilization rate (P < 0.025) and embryo quality (P < 0.001), Cytoplasm
ic criteria showed no correlation in this respect. Present data indicate th
at ICSI of oocytes with intact well-shaped first polar bodies yields higher
fertilization rates and higher quality embryos.