Stochastic properties of one-parameter discrete model of genetic diversityin the unique random parameter case

Citation
My. Shchelkanov et al., Stochastic properties of one-parameter discrete model of genetic diversityin the unique random parameter case, J BIO STRUC, 17(3), 1999, pp. 597-605
Citations number
16
Categorie Soggetti
Biochemistry & Biophysics
Journal title
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
ISSN journal
07391102 → ACNP
Volume
17
Issue
3
Year of publication
1999
Pages
597 - 605
Database
ISI
SICI code
0739-1102(199912)17:3<597:SPOODM>2.0.ZU;2-E
Abstract
Stochastic properties of previously introduced one parameter discrete model of genetic diversity (M. Yu. Shchelkanov et al, J. Biomol. Struct. Dyn. 15 , 887-894 (1998)) are investigated. Two approaches are compared: (A) when t he on-step substitution number and/or the number of substitution steps are random variables; (B) referred parameters are replaced by mathematical expe ctations of the respective variables. It has been demonstrated, that estima tions of sequence measure based on the number of replication steps are more under the assumption of case (A) as compared with (B). Thus, real biologic al situation relating to the case (A) could additionally promote the increa sing of distinctions between different taxons (e.g. HIV, etc.). Peculiariti es of one-parameter discrete model of genetic diversity during calculation of the distinctions between symbol (e.g. nucleotide) sequence sets are also discussed.