R. Cavagna et al., Macroporous calcium phosphate ceramic: A prospective study of 106 cases inlumbar spinal fusion, J LONG-TE E, 9(4), 1999, pp. 403-412
Citations number
22
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology","Medical Research Diagnosis & Treatment
Macroporous biphasic calcium phosphate (MBCP, Triosite(TM)) is well known f
or its safety absence of allergenicity, and excellent bone-bonding capacity
, and it has been widely used as a bone graft substitute in orthopaedic, EN
T, and dental surgery. This study investigates the clinical performance of
this synthetic porous ceramic in a series of 106 patients, mainly with dege
nerative spine aetiologies (95/106) and with a minimum follow-up of 2 years
. AU patients were treated with posterior correction involving the semi-rig
id New Orleans(TM) instrumentation. Spinal fusion was always performed usin
g MBCP granules mixed with autogenous bone chips and bone marrow obtained f
rom the local spine. Fusion of the spine was confirmed for 100 patients, an
d 6 non-unions were observed (3 resulting from primary spondylolisthesis).
This study shows that MBCP provides suitable results in spinal fusion invol
ving a semi-rigid instrumentation. Because the indication of degenerative s
pine is not very favorable to fusion, this technique appears to be a good a
lternative to autografts and could decrease patient morbidity resulting fro
m iliac bone grafting.