Zygosporin D and two new cytochalasins produced by the fungus Metarrhiziumanisopliae

Authors
Fujii, Y Tani, H Ichinoe, M Nakajima, H
Citation
Y. Fujii et al., Zygosporin D and two new cytochalasins produced by the fungus Metarrhiziumanisopliae, J NAT PROD, 63(1), 2000, pp. 132-135
Citations number
7
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
63
Issue
1
Year of publication
2000
Pages
132 - 135
Database
ISI
SICI code
0163-3864(200001)63:1<132:ZDATNC>2.0.ZU;2-Z
Abstract
Zygosporin D (3) and two new cytochalasins (4 and 5) were isolated from the culture filtrate of the fungus Metarrhizium anisopliae and characterized o n the basis of their spectral data and chemical conversions. The new cytoch alasins, 4 and 5, were determined to be deacetylcytochalasin C and (6R,16S, 18R,2LR)-18,21-dihydroxy-16,18-dimethyl-10-phenyl[11]cytochalasa-13(E),19(E )-diene-1,7,17-trione, respectively. Of these three cytochalasins, only zyg osporin D is an effective inhibitor of shoot elongation of rice seedlings.