POPULATION STATISTICS OF PROTEIN STRUCTURES - LESSONS FROM STRUCTURALCLASSIFICATIONS

Authors
BRENNER SE CHOTHIA C HUBBARD TJP
Citation
Se. Brenner et al., POPULATION STATISTICS OF PROTEIN STRUCTURES - LESSONS FROM STRUCTURALCLASSIFICATIONS, Current opinion in structural biology, 7(3), 1997, pp. 369-376
Citations number
54
Categorie Soggetti
Cell Biology",Biology
Journal title
Current opinion in structural biology → ACNP
ISSN journal
0959440X
Volume
7
Issue
3
Year of publication
1997
Pages
369 - 376
Database
ISI
SICI code
0959-440X(1997)7:3<369:PSOPS->2.0.ZU;2-7
Abstract
Structural classifications aid the interpretation of proteins by descr ibing degrees of structural and evolutionary relatedness. They have al so recently revealed strikingly skewed distributions at all levels; fo r example, a small number of folds are far more common than others, an d just a few superfamilies are known to have diverged widely. The clas sifications also provide an indication of the total number of superfam ilies in nature. (C) Current Biology Ltd.