The differential diagnosis of panniculitis may be challenging due to the un
iform clinical presentation of different panniculitis subsets. We describe
a 45-year-old woman with a 30 year history of panniculitis, who had repeate
dly failed to fulfill diagnostic criteria for various panniculitis subsets.
Finally, erythema induratum was diagnosed and she was successfully treated
with antituberculous chemotherapy, The wide spectrum of histological alter
ations of chronic erythema induratum as well as the sensitivity of polymera
se chain reaction for Mycobacterium tuberculosis in erythema induratum lesi
ons is discussed.