Gs. Alarcon et Aa. Bartolucci, Radiographic assessment of disease progression in rheumatoid arthritis patients treated with methotrexate or minocycline, J RHEUMATOL, 27(2), 2000, pp. 530-534
Radiographic studies of methotrexate (MTX) treated and minocycline treated
patients with rheumatoid arthritis (RA) are reviewed. A formal metaanalysis
of publications of RA treated with MTX was undertaken at the time when MTX
was used for patients with established RA. Thus the conclusions of that me
taanalysis may not be applicable to patients treated with MTX earlier in th
e course of their disease. On the other hand, there are no sufficient data
to conduct a formal metaanalysis of patients with RA treated with minocycli
ne.