A 64-year-old woman experienced progressive generalized poikiloderma after
an episode of sunburn 4 years earlier. The diagnosis of subacute cutaneous
lupus erythematosus (SCLE) was confirmed by the presence of anti-Ro/SS-A an
d antinuclear antibodies, the histology, and the direct immunofluorescent f
indings (ie, positive lupus band test and "dustlike" epidermal IgG staining
pattern). Poikiloderma has not been previously reported in the spectrum of
SCLE. As a major pathomechanism of SCLE, photosensitivity might explain th
is uncommon clinical manifestation of the disease.