Pyoderma gangrenosum and Chlamydia pneumoniae infection in a diabetic man:Pathogenic role or coincidence?

Chlamydia pneumoniae is not a known cause of skin infections, but unusual p athogens cause chronic infections in diabetic patients. Multiple idiopathic pyoderma gangrenosum-like (PG-like) lesions were refractory to multiple th erapeutic agents in a diabetic patient who had C pneumoniae identified by s erologic tests and polymerase chain reaction. Based on complete resolution by prolonged anti-chlamydial antibiotic therapy and concomitant decrease in serologic and titers determined by polymerase chain reactions, the PG-like lesions were presumed to be due to C pneumoniae.