Effect of gender on the progression of nondiabetic renal disease: A meta-analysis

There is previously published evidence that male gender is associated with a more rapid rate of progression of nondiabetic chronic renal disease. Howe ver, some investigators have concluded that no such association exists. To help resolve this issue, a meta-analysis was performed using 68 studies tha t met defined criteria and contained a total of 11,345 patients to evaluate the effect of gender on the progression of nondiabetic chronic renal disea se. The results indicate that men with chronic renal disease of various eti ologies show a more rapid decline in renal function with time than do women .