Dopamine-transporter density in nucleus accumbens of type-1 alcoholics

Authors
Tupala, E Hall, H Sarkioja, T Rasanen, P Tiihonen, J
Citation
E. Tupala et al., Dopamine-transporter density in nucleus accumbens of type-1 alcoholics, LANCET, 355(9201), 2000, pp. 380-380
Citations number
5
Categorie Soggetti
General & Internal Medicine","Medical Research General Topics
Journal title
LANCET
ISSN journal
01406736 → ACNP
Volume
355
Issue
9201
Year of publication
2000
Pages
380 - 380
Database
ISI
SICI code
0140-6736(20000129)355:9201<380:DDINAO>2.0.ZU;2-8
Abstract
We have shown that alcoholic patients have a lower number of dopamine trans porters in the nucleus accumbens, which mediates the rewarding effects of a ddictive drugs, Thus, certain dopaminergic agents may be beneficial in the treatment of alcohol withdrawal and in the long-term treatment of alcoholis m with selective use.