Vitamin C, carotenoids, and vitamin E, the three main dietary antioxidants,
each affect lipid peroxidation and may reduce atherogenesis and lower the
risk of coronary heart disease (CHD). The evidence for a cardiovascular ben
efit of antioxidants is strongest for vitamin E. This article examines this
topic further, and the authors find that, at present, the data are insuffi
cient to suggest public policy recommendations for nutritional supplementat
ion.