Tau protein function in axonal formation

Authors
Paglini, G Peris, L Mascotti, F Quiroga, S Caceres, A
Citation
G. Paglini et al., Tau protein function in axonal formation, NEUROCHEM R, 25(1), 2000, pp. 37-42
Citations number
62
Categorie Soggetti
Neurosciences & Behavoir
Journal title
NEUROCHEMICAL RESEARCH
ISSN journal
03643190 → ACNP
Volume
25
Issue
1
Year of publication
2000
Pages
37 - 42
Database
ISI
SICI code
0364-3190(200001)25:1<37:TPFIAF>2.0.ZU;2-B
Abstract
Tau protein is a predominantly neuronal microtubule-associated protein that is enriched in axons and is capable of promoting microtubule assembly and stabilization. In the present article we review some of the key experiments directed to obtain insights about tau protein function in developing neuro ns. Aspects related to whether or not tau has essential, unique, or complem entary functions during axonal formation are discussed.