SYNTHESIS OF A SERIES OF POLAR, ORTHOGONALLY PROTECTED, ALPHA,ALPHA-DISUBSTITUTED AMINO-ACIDS

Authors
YOKUM TS BURSAVICH MG PIHAPAUL SA HALL DA MCLAUGHLIN ML
Citation
Ts. Yokum et al., SYNTHESIS OF A SERIES OF POLAR, ORTHOGONALLY PROTECTED, ALPHA,ALPHA-DISUBSTITUTED AMINO-ACIDS, Tetrahedron letters, 38(23), 1997, pp. 4013-4016
Citations number
18
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
23
Year of publication
1997
Pages
4013 - 4016
Database
ISI
SICI code
0040-4039(1997)38:23<4013:SOASOP>2.0.ZU;2-2
Abstract
The synthesis of four novel, ''cationic'', alpha-alpha-disubstituted a mino acids is described. The new amino acids use an orthogonal protect ion scheme making them suitable for incorporation via solid-phase pept ide synthesis. (C) 1997 Elsevier Science Ltd.