Circumscribed choroidal hemangioma: Characteristic features with indocyanine green videoangiography

Objective: To determine the characteristic features of indocyanine green vi deoangiography (ICG-V) of circumscribed choroidal hemangioma. Design: Prospective, observational case series. Participants: Twenty-five eyes of 25 consecutive patients with circumscribe d choroidal hemangioma. Intervention: Indocyanine green videoangiography and intravenous fluorescei n angiography (IVFA) were prospectively performed and reviewed, The specifi c features on ICG-V were compared with features of IVFA. Main Outcome Measures: The behavior of circumscribed choroidal hemangioma c ases was observed with ICG-V and IVFA. Results: On ICG-V, earliest hyperfluorescence of circumscribed choroidal he mangioma was achieved at a mean of 27.6 seconds (range, 13-62 seconds), whe reas maximum hyperfluorescence occurred at 222 seconds (range, 33-707 secon ds), In the late frames, ail eyes demonstrated a relative decrease in fluor escence, including 18 eyes (72%) that demonstrated "washout" of the dye. Ot her findings on ICG-V included intrinsic vessels in 19 eyes (76%), a late h yperfluorescent rim in 19 eyes (76%), and late frame hot spots in 14 eyes ( 56%), On IVFA, the earliest hyperfluorescence was achieved at a mean of 24 seconds (range, 10-66 seconds), whereas maximum hyperfluorescence occurred at a mean of 76.3 seconds (range, 21-720 seconds). Increasing hyperfluoresc ence in the late frames was found in all cases. Other findings included int rinsic vessels in 12 eyes (48%) and hot spots in the late frames in 9 eyes (36%). Conclusions: Circumscribed choroidal hemangioma have specific characteristi cs on ICG-V that are not visualized with IVFA. We believe that ICG-V may be come an important noninvasive tool for the diagnosis of choroidal hemangiom a. (C) 2000 by the American Academy of Ophthalmology.