Polymer-supported N-tritylaziridinyl(diphenyl)methanol as an effective catalyst in the enantioselective addition of diethylzinc to aldehydes

Authors
ten Holte, P Wijgergangs, JP Thijs, L Zwanenburg, B
Citation
P. Ten Holte et al., Polymer-supported N-tritylaziridinyl(diphenyl)methanol as an effective catalyst in the enantioselective addition of diethylzinc to aldehydes, ORG LETT, 1(7), 1999, pp. 1095-1097
Citations number
18
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
1
Issue
7
Year of publication
1999
Pages
1095 - 1097
Database
ISI
SICI code
1523-7060(19991007)1:7<1095:PNAAEC>2.0.ZU;2-#
Abstract
[GRAPHICS] Novel polymer-supported N-tritylaziridino alcohol 2 was utilized as chiral ligand in the asymmetric addition of diethylzinc to aldehydes. High enantio selectivities were obtained for both aromatic and aliphatic aldehydes, The catalyst was successfully recycled and employed in subsequent additions wit h retention of high enantioselectivity.