Ar. Howell et Aj. Ndakala, Ring opening of 1,5-dioxaspiro[3.2]hexanes: Selective preparation of alpha-heterofunctionalized-beta '-hydroxy ketones or 2,2-disubstituted oxetanes, ORG LETT, 1(6), 1999, pp. 825-827
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2-Methyleneoxetanes have been converted into 1,5 dioxaspiro[3.2]hexanes wit
h dimethyldioxirane. Reaction of the dioxaspirohexanes with a range of hete
roatom nucleophiles, hydride donors, or organoaluminum reagents was success
ful under neutral or mild conditions, affording, selectively, polyfunctiona
lized ketones or 2,2 disubstituted oxetanes.