Selective azetidine and tetrahydropyridine formation via Pd-catalyzed cyclizations of allene-substituted amines and amino acids

Authors
Rutjes, FPJT Tjen, KCMF Wolf, LB Karstens, WFJ Schoemaker, HE Hiemstra, H
Citation
Fpjt. Rutjes et al., Selective azetidine and tetrahydropyridine formation via Pd-catalyzed cyclizations of allene-substituted amines and amino acids, ORG LETT, 1(5), 1999, pp. 717-720
Citations number
41
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
1
Issue
5
Year of publication
1999
Pages
717 - 720
Database
ISI
SICI code
1523-7060(19990909)1:5<717:SAATFV>2.0.ZU;2-I
Abstract
[GRAPHICS] By choosing the right substituents either highly functionalized unusual fou r-membered ring amino acids or the isomeric pipecolic acid derivatives are obtained in enantiomerically pure form. Starting material is a linear allen e containing amino acid that has been resolved via biocatalysis.