A facile method for the solution and solid-phase synthesis of substituted [3.3.1] bicycles

Citation
Kc. Nicolaou et al., A facile method for the solution and solid-phase synthesis of substituted [3.3.1] bicycles, ORG LETT, 1(5), 1999, pp. 807-810
Citations number
34
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
1
Issue
5
Year of publication
1999
Pages
807 - 810
Database
ISI
SICI code
1523-7060(19990909)1:5<807:AFMFTS>2.0.ZU;2-B
Abstract
[GRAPHICS] Interest in bicyclic natural products from the Guttiferae classification ha s led to the development of an improved method for the selenium mediated cy clization of alkenyl-substituted beta-dicarbonyls (I) to form a variety of bicyclo[3.3.1]nonan-9-ones (II) both in solution and on solid support.