The effect of allergy immunotherapy and elimination of suspected food aller
gens was evaluated in patients with Meniere's disease. A total of 137 patie
nts with Meniere's disease for whom allergy treatment had been recommended
were identified and were mailed and returned a symptoms questionnaire. One
hundred thirteen had received allergy treatment; 24 did not have treatment
and served as a control group. Information regarding history, signs and sym
ptoms, allergy test results, and audiologic data were obtained by chart rev
iew. The 113 patients treated with desensitization and diet showed a signif
icant improvement from pretreatment to posttreatment in both allergy and Me
niere's symptoms. Ratings of frequency, severity, and interference with eve
ryday activities of their Meniere's symptoms also appeared better after all
ergy treatment than ratings from the control group of untreated patients. V
ertigo control results, by use of the American Academy of Otolaryngology-He
ad and Neck Surgery classification, categorized 47.9% as class A or B. Hear
ing was stable or improved in 61.4%. Patients with Meniere's disease can sh
ow improvement in their symptoms of tinnitus and vertigo when receiving spe
cific allergy therapy. The inner ear may be the target, directly or indirec
tly, of an allergic reaction.