Fetal 'space-suit' hydrops in the first trimester: differentiating risk for chromosome abnormalities by delineating characteristics of nuchal translucency
Lp. Shulman et al., Fetal 'space-suit' hydrops in the first trimester: differentiating risk for chromosome abnormalities by delineating characteristics of nuchal translucency, PRENAT DIAG, 20(1), 2000, pp. 30-32
Citations number
14
Categorie Soggetti
Reproductive Medicine","Medical Research Diagnosis & Treatment
Detecting first trimester fetuses with pan-body hydrops, giving the appeara
nce of a 'space-suit,' is associated with a marked increased risk for chrom
osome abnormalities. In 30 consecutive fetuses prospectively characterized
by space-suit hydrops, detected at or before 13.9 weeks' gestation, 26 (86.
7%) were characterized by chromosome abnormalities. However, as opposed to
the preponderance of autosome abnormalities among first-trimester fetuses w
ith prominent nuchal translucencies, 15 of the 26 fetuses (57.7%) with abno
rmal complements were characterized by sex chromosome aneuploidies. Genetic
counselling and consideration of invasive prenatal testing is wan-anted wh
en space-suit hydrops is detected in the: first trimester. Copyright (C) 20
00 John Wiley & Sons, Ltd.