The lung is a dynamic organ that is subjected to mechanical forces througho
ut development and adult life. This review article addresses the types of m
echanical forces in the lung and their effects on development and normal lu
ng functions. The effects of mechanical forces on the various different cel
l types of the lung are discussed, as are the mechanisms underlying mechano
transduction. (C) 2000 Elsevier Science B.V. All rights reserved.