The synthesis and activity of oxazole and thiazole analogues of urocanic acid

Authors
Millan, DS Prager, RH Brand, C Hart, PH
Citation
Ds. Millan et al., The synthesis and activity of oxazole and thiazole analogues of urocanic acid, TETRAHEDRON, 56(5), 2000, pp. 811-816
Citations number
22
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
56
Issue
5
Year of publication
2000
Pages
811 - 816
Database
ISI
SICI code
0040-4020(20000128)56:5<811:TSAAOO>2.0.ZU;2-L
Abstract
Direct exposure of human skin to sunlight leads to suppression of the immun e system, believed to be mediated by urocanic acid. The synthesis of oxazol e and thiazole analogues of urocanic acid is reported, as is their effect o n biological markers of the human immune system. (C) 2000 Published by Else vier Science Ltd. All rights reserved.