Asymmetric benzoin reaction catalyzed by benzoylformate decarboxylase

Authors
Demir, AS Dunnwald, T Iding, H Pohl, M Muller, M
Citation
As. Demir et al., Asymmetric benzoin reaction catalyzed by benzoylformate decarboxylase, TETRAHEDR-A, 10(24), 1999, pp. 4769-4774
Citations number
31
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
10
Issue
24
Year of publication
1999
Pages
4769 - 4774
Database
ISI
SICI code
0957-4166(199912)10:24<4769:ABRCBB>2.0.ZU;2-M
Abstract
Aromatic aldehydes are converted into benzoins by benzoylformate decarboxyl ase catalyzed C-C bond formation. The reaction affords (R)-benzoins with hi gh enantiomeric excess and in good chemical yields. A broad range of aromat ic aldehydes can be used as substrates in aqueous buffer or buffer/DMSO-sol utions. (C) 2000 Elsevier Science Ltd. All rights reserved.