Immunophilins: Their properties and their potential role in therapeutic drug monitoring

This article reviews recent developments in the immunophilin arena and the current state of knowledge about the biochemical properties of immunophilin s. The role of immunophilin-binding assays is also explored with the conclu sion that some of these immunosuppressive-drug-binding proteins may provide better assays for sirolimus and tacrolimus than current immunoassays.