Outcome in recipients of dual kidney transplants - An analysis of the DualRegistry patients

Citation
Ad. Lu et al., Outcome in recipients of dual kidney transplants - An analysis of the DualRegistry patients, TRANSPLANT, 69(2), 2000, pp. 281-285
Citations number
23
Categorie Soggetti
Medical Research Diagnosis & Treatment
Journal title
TRANSPLANTATION
ISSN journal
00411337 → ACNP
Volume
69
Issue
2
Year of publication
2000
Pages
281 - 285
Database
ISI
SICI code
0041-1337(20000127)69:2<281:OIRODK>2.0.ZU;2-Z
Abstract
Background. A novel but controversial method to increase the utilization of aged donor kidneys is the transplantation of both kidneys as a dual transp lant. Initial single-center reports demonstrated outcomes similar to single kidneys from younger donors. In this report, we compare outcome in recipie nts of kidneys from donors greater than or equal to 54 years of age who rec eived a single kidney transplant reported to the United Network for Organ S haring Scientific Registry versus a dual kidney transplant reported to the Dual Kidney Registry. Methods. A retrospective analysis was performed, comparing four donor and n ine recipient and outcome variables between recipients of a single versus a dual transplant between March 1993 and March 1999. Results. Dual versus single transplants from donors greater than or equal t o 54 years of age have a significantly decreased incidence of delayed graft function, and lower serum creatinines up to 2 years after transplant despi te having kidneys from significantly older donors with poorer HLA matching. Conclusions. Dual kidney transplants improve graft performance and outcome in recipients of kidneys from donors greater than or equal to 54 years of a ge.