Recent progress in understanding the evolution of vertebrate genomes has be
en rapid, and previous nations that all such genomes could be regarded as e
quivalent in their gene content have been rendered outdated. This notion, o
ften embodied in the representation that vertebrates possess four Hox compl
exes, still appears in contemporary textbooks of developmental biology. Rec
ent data from the genomes of teleost fish show that this assumption is untr
ue and suggest that interesting situations might arise from the apparent pr
oliferation of genes among fish.