Several complications like hematoma and seroma have been reported afte
r laparoscopic inguinal hernia repair (LH). Sepsis due to infection of
the patch is an uncommon complication. Tn this retrospective trial, w
e evaluated three male patients who developed postoperative mesh infec
tion after LH by transabdominal preperitoneal patch (TAPP) technique i
n two institutions. Diagnosis was confirmed by clinical symptoms, sign
s, ultrasonography, and computerized tomography (CT), and definitive t
reatment was provided by removing the mesh. In the first case, mesh in
fection occurred 10 months after laparoscopic left inguinal hernia rep
air with TAPP for recurrence. The infection manifested itself as an ex
ternal fistula at the drain site. The mesh was removed laparoscopicall
y due to persistent suppuration. Tn the second case, mesh infection oc
curred 3 months after transabdominal preperitoneal hernia repair on th
e left. The patch was removed because of the persistent suppuration de
spite repetitive drainage and lavage, Tn the third case, mesh infectio
n occurred in 15 days after transabdominal preperitoneal hernia repair
on the right. External drainage was performed under CT guidance, but
suppuration could not be stopped. Thus the mesh was removed. In three
cases, infection could not be stopped after diagnosis despite drainage
and antibiotic coverage, and then it was decided to remove the mesh,
The meshes were removed under general anesthesia for the first two cas
es and under local anesthesia for the third one. During the follow-up
period. no recurrences were noted. The mesh infections of these three
cases, resistant to conservative treatment methods, completely disappe
ared after mesh removal.