Cardiac output measurements during cross-clamping of the descending thoracic aorta in pigs - A comparison between transit-time ultrasound, thermodilution and pulsed Doppler ultrasound
P. Aadahl et al., Cardiac output measurements during cross-clamping of the descending thoracic aorta in pigs - A comparison between transit-time ultrasound, thermodilution and pulsed Doppler ultrasound, ACT ANAE SC, 44(2), 2000, pp. 180-185
Citations number
36
Categorie Soggetti
Aneshtesia & Intensive Care","Medical Research Diagnosis & Treatment
Background: Cross-clamping of the descending thoracic aorta (XC) induces an
increase in cardiac output (CO). The intention of this study was to evalua
te the high CO during XC by the use of clinically available methods (thermo
dilution and pulsed Doppler ultrasound) compared to transit-time ultrasound
flowmetry of the ascending aorta as the gold standard.
Method: Ten pigs were anaesthetised with ketamine and fentanyl. The descend
ing thoracic aorta was cross-clamped for 30 min, and cardiac output was mea
sured with pulmonary artery thermodilution technique, pulsed Doppler ultras
ound on the aortic annulus and transit-time ultrasound flowmetry of the asc
ending aorta.
Results: At 15 min following XC, CO increased from 1.7 l/min to 4.6 l/min m
easured with transit-time ultrasound (P<0.05). With thermodilution techniqu
e, CO increased from 2.6 l/min to 5.7 l/min (P<0.05), and from 2.4 l/min to
6.0 l/min measured with Doppler ultrasound (P<0.05). There was an increase
in mean arterial pressure of 81% and heart rate increased 76% (P<0.05).
Conclusion: XC of the descending thoracic aorta induces an increase in CO o
f 171%. Thermodilution and pulsed Doppler ultrasound are reliable methods f
or detecting high cardiac output during thoracic aortic surgery.