The diagnosis of coronary vasospasm in chronic vasospastic angina is e
stablished by the history of typical nocturnal angina pectoris with ra
pid relief after sublingual nitroglycerin, concomitant ST-segment elev
ation on the electrocardiogram and a recent normal coronary angiogram,
True vasospasm may subsequently be confirmed on a coronary angiogram,
either spontaneously or by provokation with acethylcholine. The autho
rs show a case of acute vasospasm induced by a cold presser test in a
40-year-old man who had onset variant angina, Transient reduction of r
egional myocardial perfusion, angina pectoris at rest, and ST-segment
elevation solved after administration of nitroglycerin.