T-cell lymphoproliferative disorder of vitreous associated with mycosis fungoides

A 59-year-old man with a history of mycosis fungoides developed loss of vis ual acuity and visual field in the left eve. Epiretinal lesions were presen t in the right eye and multifocal choroidal lesions, optic disc edema, and vitritis were present in the left eye. A diagnostic vitrectomy was performe d and cytologic examination of the vitreous confirmed the diagnosis of T-ce ll lymphoproliferative disorder. Systemic and intrathecal chemotherapy resu lted in marked improvement in ocular signs and symptoms. At last follow-up, the patient was found to have improved visual acuity in the left eye; howe ver, significant worsening of his systemic condition developed and he died shortly thereafter.