Laryngeal cleft and eosinophilic gastroenteritis - Report of 2 cases

Although laryngotracheoesophageal clefts are often found in association wit h other well-described anomalies, we know of no previous reported associati on with eosinophilic gastroenteritis, a disorder of unknown etiology charac terized by eosinophilic infiltration of the gastrointestinal tract. We trea ted 2 children who had laryngeal clefts and eosinophilic gastroenteritis. S ince the esophageal inflammatory changes found in eosinophilic gastroenteri tis may persist despite aggressive therapy, management of the laryngo trach eoesophageal clefts is more complicated. The diagnosis of eosinophilic gast roenteritis should not be overlooked in patients with laryngotracheoesophag eal clefts and warrants prompt referral to a pediatric gastroenterologist.