Synthesis and H-1 NMR studies of 3-(D-erythro-glycerol-1-yl)-1H-pyrazolo[3,4-b]quinoxaline and its 7-chloro and 7-methyl analogues

Authors
Sallam, MAE Louis, FF Anthonsen, T Quartey, EGK
Citation
Mae. Sallam et al., Synthesis and H-1 NMR studies of 3-(D-erythro-glycerol-1-yl)-1H-pyrazolo[3,4-b]quinoxaline and its 7-chloro and 7-methyl analogues, CARBOHY RES, 324(1), 2000, pp. 1-9
Citations number
15
Categorie Soggetti
Agricultural Chemistry","Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
CARBOHYDRATE RESEARCH
ISSN journal
00086215 → ACNP
Volume
324
Issue
1
Year of publication
2000
Pages
1 - 9
Database
ISI
SICI code
0008-6215(20000129)324:1<1:SAHNSO>2.0.ZU;2-9
Abstract
3-(D-erythro-Glycerol-1-yl)-1H-pyrazolo[3,4-b]quinoxaline and its 7-chloro and 7-methyl analogues (11 and 12) were prepared from the corresponding qui noxalines. The 7-substituted analogues 11 and 12 were obtained as the prepo nderant isomers, and the 6-substituted analogues as the minor isomers. The structure and position of the substituent were determined by H-1 NMR studie s. The effect of substitution on the chemical shift of other protons is dis cussed. (C) 2000 Elsevier Science Ltd. All rights reserved.