1-Octanol/water distribution coefficient of oxolinic acid: influence of pHand its relation to the interaction with dissolved organic carbon

Authors
Lutzhoft, HCH Vaes, WHJ Freidig, AP Halling-Sorensen, B Hermens, JLM
Citation
Hch. Lutzhoft et al., 1-Octanol/water distribution coefficient of oxolinic acid: influence of pHand its relation to the interaction with dissolved organic carbon, CHEMOSPHERE, 40(7), 2000, pp. 711-714
Citations number
13
Categorie Soggetti
Environment/Ecology
Journal title
CHEMOSPHERE
ISSN journal
00456535 → ACNP
Volume
40
Issue
7
Year of publication
2000
Pages
711 - 714
Database
ISI
SICI code
0045-6535(200004)40:7<711:1DCOOA>2.0.ZU;2-9
Abstract
The distribution of oxolinic acid (OA) between 1-octanol and buffers at a b road range of pH values was studied and found to decrease with increasing p H. The distribution coefficient to dissolved organic carbon (DOC), log D-DO C, was estimated and compared with an experimentally derived log D-DOC, sho wing the experimental value to be almost three orders of magnitude higher. Because only the neutral molecule is assumed to distribute to 1-octanol, th e interaction with DOC is considered to be electrostatic in character. (C) 2000 Elsevier Science Ltd. All rights reserved.